Hypercapnia and surgical site infection: a randomized trial

Akca O., Kurz A., Fleischmann E., Buggy D., Herbst F., Stocchi L., ...Daha Fazla

BRITISH JOURNAL OF ANAESTHESIA, cilt.111, sa.5, ss.759-767, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 111 Sayı: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1093/bja/aet233
  • Dergi Adı: BRITISH JOURNAL OF ANAESTHESIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.759-767
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Tissue oxygenation is a strong predictor of surgical site infection (SSI). Mild intraoperative hypercapnia increases peripheral, gastrointestinal, and splanchnic tissue oxygenation and perfusion. Hypercapnia also has anti-inflammatory effects. However, it is unknown whether hypercapnia reduces SSI risk. We tested the hypothesis that mild intraoperative hypercapnia reduces the risk of SSI in patients having colon resection surgery.