Proteasomal System Related Stress Response in Different Cancer Cell Lines

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Atıf İçin Kopyala

Jannuzzi A. T., Arslan S., Alpertunga B., Yilmaz B. K.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.11, sa.1, ss.28-33, 2021 (ESCI)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 11 Sayı: 1
• Basım Tarihi: 2021
• Doi Numarası: 10.33808/clinexphealthsci.802815
• Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.28-33
• İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Proteasomal system is the primary protein degradation mechanism and important for cellular homeostasis. On the other hand, increased proteasome activity protects cancer cells from cell death. The objective of this preliminary study was to determine the response of the proteasomal system to oxidative stress in human cancer cell lines including K562 chronic myelogenous leukemia, U251 glioblastoma, DU145 prostate cancer, HepG2C3A hepatoma, and MCF7 breast cancer.