Atıf İçin Kopyala
Gokkaya B., Atasoy S., ÇIRAKOĞLU A., ARGÜDEN Y., KURU R. D., YILMAZ Ş., ...Daha Fazla
BEZMIALEM SCIENCE, cilt.10, sa.3, ss.370-375, 2022 (ESCI)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
10
Sayı:
3
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Basım Tarihi:
2022
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Doi Numarası:
10.14235/bas.galenos.2021.5638
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Dergi Adı:
BEZMIALEM SCIENCE
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Derginin Tarandığı İndeksler:
Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
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Sayfa Sayıları:
ss.370-375
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Anahtar Kelimeler:
Acute lymphoblastic leukemia, cytogenetics, fluorescence in situ hybridization, chromosome aberrations, IGH-AT TRANSLOCATIONS, GENETIC ABERRATIONS, FISH, REARRANGEMENTS, ABNORMALITIES, MORPHOLOGY, DIAGNOSIS, UTILITY, ADULTS
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İstanbul Üniversitesi Adresli:
Hayır
Özet
Objective: Acute lymphoblastic leukemia (ALL) is a disease related to the overproduction of immature lymphocytes. Fin diagnosis and classification of ALL, recognizing chromosome aberrations using conventional cytogenetic analysis (CCA) is essential. However, limited ability of CCA to capture cryptical chromosomal aberrations is a major drawback. The aim of this study was to investigate recurrent aberrations in patients with ALL with normal karyorype or unsuccessful karyoryping using the fluorescence in situ hybridization (FISH) method.