A double-blind randomized controlled trial of topiramate and amitriptyline either alone or in combination for the prevention of migraine

Keskinbora, Kader; Aydinli, Isik

doi:10.1016/j.clineuro.2008.05.025

A double-blind randomized controlled trial of topiramate and amitriptyline either alone or in combination for the prevention of migraine

Atıf İçin Kopyala

Keskinbora K., Aydinli I.

CLINICAL NEUROLOGY AND NEUROSURGERY, cilt.110, sa.10, ss.979-984, 2008 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 110 Sayı: 10
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.clineuro.2008.05.025
Dergi Adı: CLINICAL NEUROLOGY AND NEUROSURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.979-984
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Effectiveness of antidepressants and antiepileptic drugs has already been demonstrated for migraine prophylaxis as monotherapy. In the present study, the efficacy and tolerability of amitriptyline and topiramate combination is examined in the prevention of migraine attacks, in comparison to the monotherapy of each drug.