Optimisation of Ondansetron Orally Disintegrating Tablets Using Artificial Neural Networks

AKSU B., Yegen G., Purisa S., Cevher E., Ozsoy Y.

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, vol.13, no.9, pp.1379-1388, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 9
  • Publication Date: 2014
  • Doi Number: 10.4314/tjpr.v13i9.1
  • Journal Name: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1379-1388
  • Keywords: Ondansetron, Critical quality attributes, Critical process parameters, Quality target product profile, Gene expression programming, Neuro-fuzzy logic, Artificial neural network, INTELLIGENCE TECHNIQUES, NEUROFUZZY LOGIC, DESIGN, GRANULATION, FORMULATION, KNOWLEDGE, QUALITY
  • Istanbul University Affiliated: Yes

Abstract

Purpose: To investigate the impact of critical quality attributes (CQAs) and critical process parameters (CPPs) on quality target product profile (QTPP) attributes of orally disintegrating tablet (ODT) containing ondansetron (OND) using two artificial neural network (ANN) programs.