Limited effects of parsley (Petroselinum crispum) on protein glycation and glutathione in lenses of streptozotocin-induced diabetic rats


Ozcelik F., Yarat A., Yanardag R., Tunali T., Ozsoy O., Emekli N., ...More

PHARMACEUTICAL BIOLOGY, vol.39, no.3, pp.230-233, 2001 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 3
  • Publication Date: 2001
  • Doi Number: 10.1076/phbi.39.3.230.5931
  • Journal Name: PHARMACEUTICAL BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.230-233
  • Istanbul University Affiliated: Yes

Abstract

Parsley (Petroselinum crispum), which has hypoglycaemic activity, has been used as a folk remedy for diabetes. This study investigated the effect of parsley administration on diabetes-induced impairments in rat lenses. Administration of parsley extract did not prevent a decrease in glutathione nor an increase in protein glycation, although it did significantly prevent an increase in blood glucose. SDS-polyacrylamide gel electrophoresis revealed no significant differences in any protein bands between any of the groups.