Akademik Veri Yönetim Sistemi
Türkiye Klinikleri Oftalmoloji Dergisi, cilt.33, sa.2, ss.102-110, 2024 (Hakemli Dergi)
Objective: To identify prognostic factors influencing the anatomical and functional outcomes of patients undergoing combined penetrating keratoplasty (PKP) and pars plana vitrectomy (PPV) with Eckardt temporary keratoprosthesis (TKP). Material and Methods: The study is a retrospective review of cases between 2015 and 2021 at the İstanbul University, Department of Ophthalmology, where combined PPV and PKP surgeries were performed using Eckardt TKP. Demo- graphic data, etiologies, preoperative and postoperative ophthalmologic examination findings, as well as postoperative complications of the pa- tients, were recorded. Corneal graft survival rates and preoperative fac- tors that could affect survival, along with surgical methods, were analyzed. Results: In the study, 18 eyes were analyzed. The mean age of the cases was 42.4 years, and the average follow-up period was 26.9 months. Preoperatively, endophthalmitis was detected in 9 eyes (50%), retinal detachment in 8 eyes (44.4%), and choroidal detachment in one eye (9%). The total corneal allograft survival rate was 22.2%. The mean survival time of the grafts was 12.2 months, showing a significantly de- creased corneal graft survival rate in the presence of endophthalmitis (p=0.029). Conclusion: The use of temporary keratoprostheses can con- tribute to anatomical and functional success in patients undergoing com- bined PKP and PPV. It has been observed that the presence of intense inflammation, such as endophthalmitis, adversely affects corneal graft survival. It is crucial for patients to be carefully monitored for signs of corneal graft rejection and graft failure during postoperative follow-ups.