Age-related increases in plasma malondialdehyde and protein carbonyl levels and lymphocyte DNA damage in elderly subjects

Mutlu-Turkoglu U., Ilhan E., Oztezcan S., Kuru A., Aykac-Toker G., Uysal M.

CLINICAL BIOCHEMISTRY, cilt.36, sa.5, ss.397-400, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 5
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0009-9120(03)00035-3
  • Dergi Adı: CLINICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.397-400
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Objectives: Increased oxidative stress has been hypothesized to play an important role in the aging process. A role for oxidative damage in normal aging is supported by studies in experimental animals, but there is limited evidence in humans. To investigate the relationship between the oxidative stress and aging in humans, we determined lipid and protein oxidation in plasma as well as DNA damage in lymphocytes in young and elderly subjects.