Age-related increases in plasma malondialdehyde and protein carbonyl levels and lymphocyte DNA damage in elderly subjects


Mutlu-Turkoglu U., Ilhan E., Oztezcan S., Kuru A., Aykac-Toker G., Uysal M.

CLINICAL BIOCHEMISTRY, cilt.36, ss.397-400, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 36 Konu: 5
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0009-9120(03)00035-3
  • Dergi Adı: CLINICAL BIOCHEMISTRY
  • Sayfa Sayıları: ss.397-400

Özet

Objectives: Increased oxidative stress has been hypothesized to play an important role in the aging process. A role for oxidative damage in normal aging is supported by studies in experimental animals, but there is limited evidence in humans. To investigate the relationship between the oxidative stress and aging in humans, we determined lipid and protein oxidation in plasma as well as DNA damage in lymphocytes in young and elderly subjects.