Double benefit of long-acting somatostatin analogs in a patient with coexistence of acromegaly and ulcerative colitis


Yarman S., Yalin G. Y., Dogansen S. C., Canbaz B., Tanrikulu S., Akyuz F.

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, vol.41, no.5, pp.559-562, 2016 (SCI-Expanded) identifier identifier identifier

Abstract

What is known and objectiveSomatostatin analogs control GH/IGF-1 excess in acromegaly. Somatostatin receptors also mediate the complex effects of somatostatin on the gastrointestinal tract and may be defensive in inflammatory bowel diseases, such as ulcerative colitis. We present a patient who showed good response to long-acting octreotide (OCT-LAR) treatment in terms of both acromegaly and ulcerative colitis (UC).