Double benefit of long-acting somatostatin analogs in a patient with coexistence of acromegaly and ulcerative colitis


Yarman S. , Yalin G. Y. , Dogansen S. C. , Canbaz B., Tanrikulu S., Akyuz F.

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, vol.41, no.5, pp.559-562, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1111/jcpt.12412
  • Title of Journal : JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
  • Page Numbers: pp.559-562

Abstract

What is known and objectiveSomatostatin analogs control GH/IGF-1 excess in acromegaly. Somatostatin receptors also mediate the complex effects of somatostatin on the gastrointestinal tract and may be defensive in inflammatory bowel diseases, such as ulcerative colitis. We present a patient who showed good response to long-acting octreotide (OCT-LAR) treatment in terms of both acromegaly and ulcerative colitis (UC).