Can ebselen prevent cisplatin-induced ovarian damage?

SOYMAN Z., Uzun H., Bayindir N., EŞREFOĞLU M., BORAN B.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.297, no.6, pp.1549-1555, 2018 (SCI-Expanded) identifier identifier identifier


Purpose The occurrence of ovarian damage is a major shortcoming in treating tumors with cisplatin (CP). The present study investigates the beneficial effects of ebselen-a seleno-organic compound with antioxidant and antiinflammatory properties-vis-a-vis CP-induced ovarian damage.