Can ebselen prevent cisplatin-induced ovarian damage?

SOYMAN Z., Uzun H., Bayindir N., EŞREFOĞLU M., BORAN B.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.297, sa.6, ss.1549-1555, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 297 Sayı: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s00404-018-4750-4
  • Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1549-1555
  • İstanbul Üniversitesi Adresli: Evet

Özet

Purpose The occurrence of ovarian damage is a major shortcoming in treating tumors with cisplatin (CP). The present study investigates the beneficial effects of ebselen-a seleno-organic compound with antioxidant and antiinflammatory properties-vis-a-vis CP-induced ovarian damage.