The process of globalization has and has given countries change and transformation in economic, political and social fields.The social policies and labor relations institutions of the countries are also affected by this transformation of globalization. Due to the new production and management techniques that emerged with the globalization process, a negative environment emerged for the trade unions, one of the most important actors in industrial relations. As a matter of fact, it is seen that the multinational companies whose effectiveness is increasing in the process are now going to transnational organization rather than being organized locally. The collective voice mechanism, which is the most important power of the unions, and the aspirations to organize on a global scale have existed since the years of the industrial revolution. However, it is possible to say that today, unions have fulfilled these demands only by being organized under the umbrella of a higher organization on a global level. Global top trade union organizations focus not only on the problems between workers and employers in working life, but also on the problems of other disadvantaged groups in social life. The main purpose of this study is to examine the role of the ETUC in the European Union. During the globalization process, ETUC has undergone various changes and transformations. The aim of the ETUC is to ensure the coordination of workers ‘movements at European level and to organize these workers’ movements under one roof. While maintaining this aim, it continues to be a regional power. In this study, the changes of the ETUC in the globalization process will be discussed and the organization strategy of ETUC will be tried to be determined.