Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities
Journal of Research in Pharmacy, vol.28, no.3, pp.630-640, 2024 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 28 Issue: 3
- Publication Date: 2024
- Doi Number: 10.29228/jrp.724
- Journal Name: Journal of Research in Pharmacy
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.630-640
- Keywords: acetylcolinesterase, antimicrobial, antioxidant, Helichrysum armenium subsp. armenium, LC-HRMS, phenolic compounds
- Open Archive Collection: AVESIS Open Access Collection
- Istanbul University Affiliated: Yes
Abstract
Helichrysum armenium subsp. armenium plant was extracted with the Soxhlet apparatus. The obtained extract was fractionated and, respectively, AHB (petroleum ether–60% ethanol-chloroform), AHC (ethanol-toluene), AHD (ethanol-chloroform), and AHE (ethanol-ethylacetate) extracts were obtained. Then, antimicrobial, antioxidant, and acetylcholinesterase activity studies were performed on these extracts. In this study, with the using the LC-HRMS method from the aerial parts of Helichrysum armenium subsp. armenium, the flavonoids: apigenin, apigenin 7-glucoside, apigenin 7-methylate, luteolin 7-glucoside, kaempferol, quercetin, quercitrin, (+)-trans taxifolin, (-)-epicatechin gallate, sinensetin, rutin, 3'-o-methyl quercetin, hispidulin, chrysin, acacetin, genkwanin, chrysoeriol; the phenolic acids: chlorogenic acid, ascorbic acid, fumaric acid, caffeic acid, salicylic acid, caffeic acid phenethyl ester, emodin, vanilic acid; the alkaloid: caffeine and the saponoside; glycyrrhizic acid were obtained.