Acute disseminated encephalomyelitis (ADEM) after pertussis infection


Budan B., Ekici B., Tatli B., Somer A.

ANNALS OF TROPICAL PAEDIATRICS, cilt.31, sa.3, ss.269-272, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1179/1465328111y.0000000028
  • Dergi Adı: ANNALS OF TROPICAL PAEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.269-272
  • İstanbul Üniversitesi Adresli: Evet

Özet

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated demyelinating disorder of the central nervous system which is usually precipitated by a viral infection or vaccination. A 3-month-old boy is reported who developed ADEM a week after full recovery from pertussis. MRI detected a high-intensity lesion extending from the pons to the mesencephalon, compatible with ADEM. Following the administration of intravenous immunoglobulins, the patient's clinical symptoms improved. This case report demonstrates that pertussis is capable of inducing an immune-mediated demyelinating disorder of the central nervous system.