THE ASSOCIATION OF RETICULATED THROMBOCYTE COUNT WITH TREATMENT RESPONSE IN PATIENTS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.83, no.2, pp.138-145, 2020 (ESCI, TRDizin)
- Publication Type: Article / Article
- Volume: 83 Issue: 2
- Publication Date: 2020
- Doi Number: 10.26650/iuitfd.2018.0042
- Journal Name: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
- Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Page Numbers: pp.138-145
- Istanbul University Affiliated: No
Abstract
Objective: Idiopathic thrombocytopenic purpura (ITP) causes thrombocytopenia via the premature destruction of autoantibody covered thrombocytes. It is diagnosed by exclusion of other diseases which cause thrombocytopenia. Reticulothrom-bocytes (RT) are young thrombocytes containing messenger ribonucleic acid (mRNA) and ribosomal ribonucleic acid (rRNA). Measurement of RT with flow cytometry is reported to reflect thrombopoetic activity in thrombocytopenic patients.