THE ASSOCIATION OF RETICULATED THROMBOCYTE COUNT WITH TREATMENT RESPONSE IN PATIENTS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA


Artan A. S. , Nalcaci M.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.83, ss.138-145, 2020 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 83 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.26650/iuitfd.2018.0042
  • Dergi Adı: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
  • Sayfa Sayıları: ss.138-145

Özet

Objective: Idiopathic thrombocytopenic purpura (ITP) causes thrombocytopenia via the premature destruction of autoantibody covered thrombocytes. It is diagnosed by exclusion of other diseases which cause thrombocytopenia. Reticulothrom-bocytes (RT) are young thrombocytes containing messenger ribonucleic acid (mRNA) and ribosomal ribonucleic acid (rRNA). Measurement of RT with flow cytometry is reported to reflect thrombopoetic activity in thrombocytopenic patients.