World Dental Congress 2024 |FDI, İstanbul, Türkiye, 12 - 15 Eylül 2024, cilt.74, ss.67
Peripheral Giant Cell Granuloma: Case Series and Treatment Approaches
Introduction
Peripheral giant cell granuloma (PGCG) is a benign, reactive, exophytic lesion of the oral cavity, commonly observed in females, primarily within the mandible, and most frequently among individuals aged between 40 and 60 years.
Case Description
This study presents a case series involving 10 patients aged between 7 and 68 years (F/M: 5/5, mean age: 42.5 years) who developed PGCG. The lesions were predominantly located in the mandible (7 cases) and less frequently in the maxilla (3 cases), arising due to factors such as inadequate oral hygiene, traumatic tooth extractions, incompatible prostheses, and chronic trauma. Lesion sizes ranged from 0.5 cm to 3 cm in diameter. Local anesthesia was administered for lesion excision, with some cases requiring additional cautery or laser treatment for bleeding control. Extraction of teeth associated with the lesions was necessary in 3 cases. During the follow-up period, which ranged from 2 to 10 years for all patients, recovery was uneventful, and no recurrence was observed.
Discussion
The management of PGCG involves eliminating causative factor(s) and locally surgically excising the lesion. In cases where the periodontal ligament is involved, extraction of the associated teeth is also considered part of the treatment plan. Oral hygiene deficiency was identified as a general etiological factor in our case series, leading to the provision of oral hygiene education to all patients.
Conclusion
Early diagnosis and management of PGCG are essential to prevent damage to adjacent periodontal tissues and teeth. Therefore, eliminating etiological factors and ensuring regular follow-up appointments for patients are crucial due to the potential for recurrence.
Keywords: Peripheral giant cell granuloma (PGCG), oral hygiene inadequacy, local surgical excision