Research Information System
Istanbul University Press, İstanbul, 2024
Pharmacogenetics is the study of different responses to disease susceptibility and drug response in individuals according to their genetic characteristics. The genetic structure can affect drug metabolism, pharmacokinetics and pharmacodynamics. Pharmacogenetics, which determines the relationship between genetics and drug response and the differences between individuals, allows the safest and most appropriate treatment to be planned individually. This method is especially prominent when creating a treatment plan for cancer patients. Oncologic treatments often cause serious side effects in patients and may cause treatment to be interrupted. In the light of pharmacogenetics information, it can be determined which chemotherapeutic will treat the patient most effectively and safely according to the patient’s genetic structure. Research in recent years has contributed to the treatment planning of many patients in the clinic. However, since it is still a developing field, many studies are still needed to resolve the link between drug response and genetic structure.