Attenuation of acute lung injury following lower limb ischemia/reperfusion: the pharmacological approach

KOKSAL C., BOZKURT A. K., USTUNDAG N., KONUKOGLU D., Musellim B., SIRIN G., ...More

JOURNAL OF CARDIOVASCULAR SURGERY, vol.47, no.4, pp.445-449, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 4
  • Publication Date: 2006
  • Journal Name: JOURNAL OF CARDIOVASCULAR SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.445-449
  • Istanbul University Affiliated: Yes

Abstract

Aim. The purpose of this study was to examine the effects of N-acetylcysteine (NAC), calcium dobesilate (DOBE) and aprotinin on the amelioration of lung damage following ischemia/reperfusion injury in a rat hind limb model. A well known antioxidant dimethyl-sulfoxide (DMSO) was also tested for comparison.