Antiglycation and anti-oxidant efficiency of carnosine in the plasma and liver of aged rats


Binguel I., Yilmaz Z., Aydin A. F. , Coban J., Dogru-Abbasoglu S. , Uysal M.

GERIATRICS & GERONTOLOGY INTERNATIONAL, cilt.17, ss.2610-2614, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 17 Konu: 12
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/ggi.13126
  • Dergi Adı: GERIATRICS & GERONTOLOGY INTERNATIONAL
  • Sayfa Sayıları: ss.2610-2614

Özet

AimIncreases in oxidative stress and advanced glycation end-products (AGE) formation play an important role in the pathogenesis of aging. Carnosine (CAR; -alanyl-L-histidine) has anti-oxidant and antiglycating properties. We investigated the effect of CAR supplementation on AGE levels, and protein and lipid oxidation products in the serum and liver tissue in aged rats.