Increased risk for kidney sequelae surrogates in survivors of Wilms tumor


Arslan E., SAYGILI S. K., Celkan T. T., Kurugoglu S., Elicevik M., Camcioglu A. E., ...More

PEDIATRIC NEPHROLOGY, vol.37, no.10, pp.2415-2426, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 10
  • Publication Date: 2022
  • Doi Number: 10.1007/s00467-022-05460-1
  • Journal Name: PEDIATRIC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.2415-2426
  • Keywords: Albuminuria, ABPM, Biomarkers, Chronic kidney disease, Sequelae, Wilms tumor, GELATINASE-ASSOCIATED LIPOCALIN, ACID-BINDING PROTEIN, STAGE RENAL-DISEASE, BLOOD-PRESSURE, ESTIMATING GFR, CYSTATIN C, CHILDREN, NEPHRECTOMY, SIZE, MICROALBUMINURIA
  • Istanbul University Affiliated: Yes

Abstract

Background There is evidence of increased risk of hypertension, albuminuria, and development of chronic kidney disease (CKD) in long-term follow-up of survivors of Wilms tumor (WT). However, most studies were conducted in heterogeneous groups, including patients with solitary kidney. In addition, little is known about tubular dysfunction. This study aimed to investigate kidney sequelae, including CKD development, hypertension, and glomerular and tubular damage in WT survivors.