A Malignant Transformation of a Spinal Epidural Mass from Ganglioneuroblastoma to Neuroblastoma


Akcakaya M. O. , Bilgic B. , Aras Y. , Izgi N.

JOURNAL OF KOREAN NEUROSURGICAL SOCIETY, cilt.57, ss.211-214, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 57 Konu: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3340/jkns.2015.57.3.211
  • Dergi Adı: JOURNAL OF KOREAN NEUROSURGICAL SOCIETY
  • Sayfa Sayıları: ss.211-214

Özet

Ganglioneuromas are benign tumors. Surgical excision is the treatment of choice with very good prognosis. However, neuroblastomatous malignant transformation of ganglioneuromas was previously reported. We report a patient with spinal neuroblastoma recurrent from a ganglioneuroblastoma after disease free survival of 13 years. This is one of the rare examples of spinal neuroblastoma and to our knowledge the second case report with malignant transformation from a ganglioneuroblastoma or a ganglioneuroma. The present case is the only report in the literature with further genetic investigations.