Relationship between fecal calprotectin level and disease activity in patients with hidradenitis suppurativa

Eser E., Engin B., YÜKSEL MAYDA P., Kocazeybek B. S., Kutlubay Z., Serdaroglu S., ...Daha Fazla

DERMATOLOGIC THERAPY, cilt.33, sa.2, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1111/dth.13232
  • Dergi Adı: DERMATOLOGIC THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: calprotectin, disease activity, hidradenitis suppurativa
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background Hidradenitis suppurativa is a chronic, inflammatory, recurrent disease with recurrent abscesses, and sinus tract formation leading to scarring. Calprotectin has immunomodulatory, antimicrobial, and antiproliferative properties and is a calcium-binding protein primarily found in the neutrophil cytoplasm. In recent years, a significant relationship between the activity of various diseases and the level of calprotectin has led to the conclusion that there may be a similar relationship in hidradenitis suppurativa.