Relationship between fecal calprotectin level and disease activity in patients with hidradenitis suppurativa


Eser E., Engin B., YÜKSEL MAYDA P., Kocazeybek B. S. , Kutlubay Z., Serdaroglu S., ...More

DERMATOLOGIC THERAPY, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2020
  • Doi Number: 10.1111/dth.13232
  • Journal Name: DERMATOLOGIC THERAPY
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database

Abstract

Background Hidradenitis suppurativa is a chronic, inflammatory, recurrent disease with recurrent abscesses, and sinus tract formation leading to scarring. Calprotectin has immunomodulatory, antimicrobial, and antiproliferative properties and is a calcium-binding protein primarily found in the neutrophil cytoplasm. In recent years, a significant relationship between the activity of various diseases and the level of calprotectin has led to the conclusion that there may be a similar relationship in hidradenitis suppurativa.