The role of bicarbonate precursors in balanced fluids during haemorrhagic shock with and without compromised liver function

Ergın B., Kapucu A., Guercı P., Ince C. H.

BRITISH JOURNAL OF ANAESTHESIA, cilt.117, ss.521-528, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 117
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1093/bja/aew277
  • Dergi Adı: BRITISH JOURNAL OF ANAESTHESIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.521-528
  • Anahtar Kelimeler: buffered solution, gluconate, haemorrhagic shock, microcirculation, PlasmaLyte, INTENSIVE-CARE, HYDROXYETHYL STARCH, PLASMA-LYTE, RESUSCITATION, ACETATE, LACTATE, SALINE, MULTICENTER, GLUCONATE, PO-2
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Lactate, acetate, and gluconate are anions used in balanced resuscitation fluids, of which lactate and acetate are considered bicarbonate precursors. This study investigated the role of the liver in the ability of balanced and unbalanced solutions to correct acid base alterations and renal haemodynamics and microvascular oxygenation in a rat model of resuscitated haemorrhagic shock.