AMERICAN JOURNAL OF PERINATOLOGY, cilt.38, sa.10, ss.1062-1069, 2021 (SCI-Expanded)
Objective The aim of this study is to assess the effects of administering 20mg/kg loading dose of caffeine citrate intravenously on splanchnic oxygenation in preterm infants. Study Design The infants with a gestational age (GA) of <34 weeks who were administered with a 20mg/kg intravenous loading dose of caffeine citrate within 48hours after birth were investigated prospectively. Regional splanchnic oxygen saturation (rsSO (2) ) and splanchnic fractional tissue oxygen extraction rate (sFTOE) were measured using near-infrared spectroscopy before caffeine infusion, immediately after caffeine infusion and 1, 2, 3, 4, and 6hours (h) after dose completion; postdose values were compared with predose values. Results A total of 41 infants with a mean GA of 29.21.6 weeks and birth weight of 1,315