IMPLICATION OF SERUM IL-17 LEVELS IN CHRONIC HEPATITIS B PATIENTS
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.84, no.1, pp.68-75, 2021 (ESCI, TRDizin)
- Publication Type: Article / Article
- Volume: 84 Issue: 1
- Publication Date: 2021
- Doi Number: 10.26650/iuitfd.2020.0094
- Journal Name: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
- Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Page Numbers: pp.68-75
- Keywords: Hepatitis B virus, Chronic hepatitis B, Fibrosis stage, Interleukin-17, INCREASED TH17 CELLS, DISEASE PROGRESSION, LIVER FIBROSIS, STELLATE CELLS, INFLAMMATION, EXPRESSION, CONTRIBUTE, FREQUENCY, SEVERITY, THERAPY
- Open Archive Collection: AVESIS Open Access Collection
- Istanbul University Affiliated: Yes
Abstract
Objective: Natural course and clinical outcomes of chronic hepatitis B virus (HBV) infection is closely releated to immun responses of host and viral factors. Studies have suggested that there is strongly correlation between the level of IL-17 and especially of advanced liver damages associated with HBV. Role of IL-17 on natural course of chronic hepatitis B disease is yet to be fully clarified. This study aimed to evaluate the correlation between serum IL-17 levels with histological, virological, serological and biochemical data of chronic hepatitis B patients.