Human Leukocyte Antigen and Major Histocompatibility Complex Class I-Related Chain A Antibodies After Kidney Transplantation in Turkish Renal Transplant Recipients

Seyhun, Y.; Ozdilli, K.; Oguz, Fatma; Karahan, Gonca; Onal, Ayşe; Turkmen, A.; Eldegez, U.; Nane, İsmet; Caliskan, Y.; Bakkaloglu, Hüseyin; Çarin, Mahmut

doi:10.1016/j.transproceed.2012.04.018

Human Leukocyte Antigen and Major Histocompatibility Complex Class I-Related Chain A Antibodies After Kidney Transplantation in Turkish Renal Transplant Recipients

Atıf İçin Kopyala

Seyhun Y., Ozdilli K., Oguz F., Karahan G., Onal E., Turkmen A., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.44, ss.1660-1666, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 44
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.transproceed.2012.04.018
Dergi Adı: TRANSPLANTATION PROCEEDINGS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1660-1666
İstanbul Üniversitesi Adresli: Evet

Özet

Background. This study was designed to determine whether human leukocyte antigen (HLA) and major histocompatibility complex class I chain-related A (MICA) antibody (Ab) production during the first 6 months posttransplantation correlated with long-term graft survival and rejection rate. The study group included 147 first transplantations from either living related (LRDs) or deceased donors (DDs) who were divided into two subgroups: rejection (RG, n = 28) and nonrejection (NRG, n = 119). Serum samples (n = 441) collected from each patient on posttransplant days 30, 90, and 180 were tested for HLA and MICA Ab using the Luminex technique.