Co-existence of multiple sclerosis and anti-NMDA receptor encephalitis: A case report and review of literature.
Multiple sclerosis and related disorders, vol.42, pp.102075, 2020 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 42
- Publication Date: 2020
- Doi Number: 10.1016/j.msard.2020.102075
- Journal Name: Multiple sclerosis and related disorders
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Page Numbers: pp.102075
- Keywords: Multiple sclerosis, NMDAR encephalitis, Overlapping demyelinating syndromes, D-ASPARTATE RECEPTOR, EBV, PATIENT
- Istanbul University Affiliated: Yes
Abstract
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a serious autoimmune disorder characterized by psychiatric symptoms, seizures and movement disorder. Predisposing factors have been reported since the time it was described, and its pathophysiology has been tried to be clarified over the years. Although overlap with other demyelinating diseases had been reported, such an association between Multiple Sclerosis (MS) anti ANT?- NMDAR encephalitis is limited to only a few case reports. In this article, a patient diagnosed with relapsing remitting multiple sclerosis (RRMS) for ten years who then developed NMDA-R encephalitis while on disease modifying treatment will be presented and possible common pathophysiology with previously reported litera- ture will be discussed.