Co-existence of multiple sclerosis and anti-NMDA receptor encephalitis: A case report and review of literature.

Gulec B., Kurucu H., Bozbay S., Dikmen Y., Sayman H., Tuzun E., ...Daha Fazla

Multiple sclerosis and related disorders, cilt.42, ss.102075, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.msard.2020.102075
  • Dergi Adı: Multiple sclerosis and related disorders
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.102075
  • Anahtar Kelimeler: Multiple sclerosis, NMDAR encephalitis, Overlapping demyelinating syndromes, D-ASPARTATE RECEPTOR, EBV, PATIENT
  • İstanbul Üniversitesi Adresli: Evet

Özet

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a serious autoimmune disorder characterized by psychiatric symptoms, seizures and movement disorder. Predisposing factors have been reported since the time it was described, and its pathophysiology has been tried to be clarified over the years. Although overlap with other demyelinating diseases had been reported, such an association between Multiple Sclerosis (MS) anti ANT?- NMDAR encephalitis is limited to only a few case reports. In this article, a patient diagnosed with relapsing remitting multiple sclerosis (RRMS) for ten years who then developed NMDA-R encephalitis while on disease modifying treatment will be presented and possible common pathophysiology with previously reported litera- ture will be discussed.