Increased costimulatory molecule expression of thymic and peripheral B cells and a sensitivity to IL-21 in myasthenia gravis

Hocaoglu, Mehmet; Durmus, Hacer; Ozkan, Berker; Yentur, Sibel; Dogan, Oner; Parman, Yesim; Deymeer, Feza; Saruhan-Direskeneli, Güher

doi:10.1016/j.jneuroim.2018.07.006

Increased costimulatory molecule expression of thymic and peripheral B cells and a sensitivity to IL-21 in myasthenia gravis

Hocaoglu M., Durmus H., Ozkan B., Yentur S. P., Dogan O., Parman Y., ...Daha Fazla

JOURNAL OF NEUROIMMUNOLOGY, cilt.323, ss.36-42, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 323
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.jneuroim.2018.07.006
Dergi Adı: JOURNAL OF NEUROIMMUNOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.36-42
Anahtar Kelimeler: Myasthenia gravis, B cells, Thymus, IL-21, Co-stimulation, SELF-ANTIGENS, MEMORY, SCLEROSIS, THYMOMA
İstanbul Üniversitesi Adresli: Evet

Özet

B cells may contribute to the pathogenesis of myasthenia gravis with anti-acetylcholine antibodies (AChR + MG) by co-stimulation or selection of T cells.