Increased costimulatory molecule expression of thymic and peripheral B cells and a sensitivity to IL-21 in myasthenia gravis


Hocaoglu M., Durmus H., Ozkan B., Yentur S. P., Dogan O., Parman Y., ...More

JOURNAL OF NEUROIMMUNOLOGY, vol.323, pp.36-42, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 323
  • Publication Date: 2018
  • Doi Number: 10.1016/j.jneuroim.2018.07.006
  • Journal Name: JOURNAL OF NEUROIMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.36-42
  • Keywords: Myasthenia gravis, B cells, Thymus, IL-21, Co-stimulation, SELF-ANTIGENS, MEMORY, SCLEROSIS, THYMOMA
  • Istanbul University Affiliated: Yes

Abstract

B cells may contribute to the pathogenesis of myasthenia gravis with anti-acetylcholine antibodies (AChR + MG) by co-stimulation or selection of T cells.