The EANM guideline for radiosynoviorthesis

Kampen W. U., Boddenberg-Paetzold B., Fischer M., Gabriel M., Klett R., Konijnenberg M., ...More

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, vol.49, no.2, pp.681-708, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.1007/s00259-021-05541-7
  • Journal Name: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Biotechnology Research Abstracts, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.681-708
  • Keywords: Synovitis, Arthritis, Radiosynoviorthesis, MODIFYING ANTIRHEUMATIC DRUGS, CHRONIC HEMOPHILIC SYNOVITIS, UPPER EXTREMITY JOINTS, LONG-TERM EVALUATION, NERVE GROWTH-FACTOR, RADIATION SYNOVECTOMY, RHEUMATOID-ARTHRITIS, RADIONUCLIDE SYNOVECTOMY, BIOLOGICAL DOSIMETRY, Y-90 SYNOVECTOMY
  • Istanbul University Affiliated: Yes

Abstract

Purpose Radiosynoviorthesis (RSO) using the intraarticular application of beta-particle emitting radiocolloids has for decades been used for the local treatment of inflammatory joint diseases. The injected radiopharmaceuticals are phagocytized by the superficial macrophages of the synovial membrane, resulting in sclerosis and fibrosis of the formerly inflamed tissue, finally leading to reduced joint effusion and alleviation of joint pain.