Role of Immunohistochemistry in the Differential Diagnosis of Pediatric Renal Tumors: Expression of Cyclin D1, Beta-Catenin , PDGFR-Alpha, and PTEN


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Kepil N., Batur S., Kain Z. E., Ozcan G., Şenol Y. E., Ozcan R., ...More

TURKISH JOURNAL OF PATHOLOGY, vol.38, no.2, pp.83-89, 2022 (ESCI) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.5146/tjpath.2022.01568
  • Journal Name: TURKISH JOURNAL OF PATHOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.83-89
  • Keywords: Cyclin D1, Immunohistochemistry, Pediatric pathology, Renal tumors, Wilms tumor, CLEAR-CELL SARCOMA, WILMS-TUMOR, PATHWAY, IMMUNOREACTIVITY, ACTIVATION
  • Istanbul University Affiliated: Yes

Abstract

Objective: Pediatric renal tumors overlap histomorphologically and may cause misdiagnosis. We aimed to determine the role of immunohistochemical staining of Cyclin D1, PTEN, beta-catenin and PDGFR-alpha on pediatric renal tumors.