Role of Immunohistochemistry in the Differential Diagnosis of Pediatric Renal Tumors: Expression of Cyclin D1, Beta-Catenin , PDGFR-Alpha, and PTEN

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Kepil N., Batur S., Kain Z. E. , Ozcan G., Şenol Y. E. , Ozcan R., ...More

TURKISH JOURNAL OF PATHOLOGY, vol.38, no.2, pp.83-89, 2022 (ESCI)

• Publication Type: Article / Article
• Volume: 38 Issue: 2
• Publication Date: 2022
• Doi Number: 10.5146/tjpath.2022.01568
• Journal Name: TURKISH JOURNAL OF PATHOLOGY
• Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals
• Page Numbers: pp.83-89
• Keywords: Cyclin D1, Immunohistochemistry, Pediatric pathology, Renal tumors, Wilms tumor, CLEAR-CELL SARCOMA, WILMS-TUMOR, PATHWAY, IMMUNOREACTIVITY, ACTIVATION
• Istanbul University Affiliated: Yes

Abstract

Objective: Pediatric renal tumors overlap histomorphologically and may cause misdiagnosis. We aimed to determine the role of immunohistochemical staining of Cyclin D1, PTEN, beta-catenin and PDGFR-alpha on pediatric renal tumors.