The impact of platelet membrane glycoprotein Ib alpha and Ia/IIa polymorphisms on the risk of thrombosis in the antiphospholipid syndrome


Yonal I. , Hindilerden F., Hancer V. S. , Artim-Esen B. , Daglar A. , Akadam B., ...Daha Fazla

Thrombosis Research, cilt.129, ss.486-491, 2012 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 129 Konu: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.thromres.2011.10.005
  • Dergi Adı: Thrombosis Research
  • Sayfa Sayıları: ss.486-491

Özet

Background: Pathogenesis of thrombus formation in antiphospholipid syndrome (APS) is not clear. Platelet membrane glycoprotein (GP) receptors play important roles in development of thrombosis. Objectives: We investigated the association between development of thrombosis in APS and polymorphisms of GPIb alpha variable number of tandem repeats (VNTR), Kozak, and GPIa C807T.