The impact of platelet membrane glycoprotein Ib alpha and Ia/IIa polymorphisms on the risk of thrombosis in the antiphospholipid syndrome

Yonal, İPEK; Hindilerden, Fehmi; Hancer, Veysel; Artim-Esen, BAHAR; Daglar, AYNUR; Akadam, Basak; Nalcaci, Meliha; Diz-Kucukkaya, Reyhan

doi:10.1016/j.thromres.2011.10.005

The impact of platelet membrane glycoprotein Ib alpha and Ia/IIa polymorphisms on the risk of thrombosis in the antiphospholipid syndrome

Yonal I., Hindilerden F., Hancer V. S., Artim-Esen B., Daglar A., Akadam B., ...Daha Fazla

Thrombosis Research, cilt.129, sa.4, ss.486-491, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 129 Sayı: 4
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.thromres.2011.10.005
Dergi Adı: Thrombosis Research
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.486-491
İstanbul Üniversitesi Adresli: Evet

Özet

Background: Pathogenesis of thrombus formation in antiphospholipid syndrome (APS) is not clear. Platelet membrane glycoprotein (GP) receptors play important roles in development of thrombosis. Objectives: We investigated the association between development of thrombosis in APS and polymorphisms of GPIb alpha variable number of tandem repeats (VNTR), Kozak, and GPIa C807T.