Efficacy of alpha interferon therapy for lamivudine resistance in chronic hepatitis B

Danalioglu, A; Kaymakoglu, S; Cakaloglu, Y; Demir, K; Karaca, Çetin; Durakoglu, Z; Bozaci, M; Badur, Osman; Cevikbas, U; Okten, A

doi:10.1111/j.1368-5031.2004.00011.x

Efficacy of alpha interferon therapy for lamivudine resistance in chronic hepatitis B

Danalioglu A., Kaymakoglu S., Cakaloglu Y., Demir K., Karaca C., Durakoglu Z., ...More

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, vol.58, no.7, pp.659-661, 2004 (SCI-Expanded)

Publication Type: Article / Article
Volume: 58 Issue: 7
Publication Date: 2004
Doi Number: 10.1111/j.1368-5031.2004.00011.x
Journal Name: INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.659-661
Istanbul University Affiliated: Yes

Abstract

Objectives: The occurrence of lamivudine resistance is often associated with the clinical breakthrough, which is characterised by the reappearance of hepatitis B virus (HBV) DNA in serum and the elevation of aminotransferases. We evaluated the efficacy of alpha interferon for clinical breakthrough in patients receiving lamivudine therapy.