Independent lesions of fixed drug eruption caused by trimethoprim-sulfamethoxazole and tenoxicam in the same patient: A rare case of polysensitivity

Ozkaya-Bayazit, Esen

doi:10.1016/j.jaad.2004.01.062

Independent lesions of fixed drug eruption caused by trimethoprim-sulfamethoxazole and tenoxicam in the same patient: A rare case of polysensitivity

Atıf İçin Kopyala

Ozkaya-Bayazit E.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, cilt.51, sa.2, 2004 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 51 Sayı: 2
Basım Tarihi: 2004
Doi Numarası: 10.1016/j.jaad.2004.01.062
Dergi Adı: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
İstanbul Üniversitesi Adresli: Evet

Özet

Polysensitivity in fixed drug eruption is a rare finding that occurs because of chemically unrelated drugs. In cases of polysensitivity, the lesions may occur on identical or separate sites, the latter indicating the role of antigen-specific mechanisms in the site-specificity of fixed drug eruption. I herein report a patient with separate site involvement induced by trimethoprim-sulfamethoxazole and tenoxicam, a drug combination that has not been reported before. Reactivation of old trimethoprim-sulfamethoxazole-specific lesions after a long resting period was another striking feature.