Contribution of SPECT-CT in the Differentiation of Ectopic Thyroid Tissue and Thyroglossal Duct Cyst


Deniz G., Işık E. G., Has Şimşek D., Şanlı Y., Arça B., Kuyumcu S.

EANM'23, Vienna, Avusturya, 9 - 13 Eylül 2023, ss.793

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Doi Numarası: 10.1007/s00259-023-06451-6
  • Basıldığı Şehir: Vienna
  • Basıldığı Ülke: Avusturya
  • Sayfa Sayıları: ss.793
  • İstanbul Üniversitesi Adresli: Evet

Özet

Aim/Introduction: 

The thyroid gland forms between the first and second pharyngeal sacs, near the base of the tongue. During migration, the thyroid tissue may remain attached anywhere along the thyroglossal duct. However, thyroglossal duct cysts and ectopic thyroid tissue can be difficult to detect using methods such as USG and planar scintigraphy. To detect the presence of ectopic/pyramidal thyroid tissue in the thyroglossal duct and to determine the anatomical localization of the thyroid tissue, Tc99m-pertechnetate SPECT-CT can be used. In this case, we aimed to detect ectopic/pyramidal thyroid tissue with SPECT-CT.

Case Presentation: 

A 41-year-old female patient, who had a subtotal thyroidectomy 20 years ago, was referred to us with a complaint of swelling in the neck. In previous thyroid ultrasound (USG) imaging, it was not possible to distinguish between ectopic thyroid tissue and thyroglossal duct cyst in the anterior region of the neck, located superior to the thyroid gland.  Thyroid scintigraphy and SPECT-CT imaging were performed using Tc99m-pertechnetate. Uptake was observed in the thyroid bed, consistent with residual thyroid tissue on the right. Additionally, in SPECT CT, the patient exhibited activity involvement due to lobulated ectopic/pyramidal thyroid tissue starting from the infrahyoid region and extending to the lower level of the thyroid cartilage with no thyroglossal cyst. 

Conclusion: 

Thyroid tissue can also be found in other parts of the descending tract, where thyroglossal duct cysts can be observed. However, the probability of ectopic thyroid in the cyst wall is less than 5%. While it does produce thyroid hormones, its concentrations are often below normal.1 2  In our case report, tracer involvement was observed in the anterior midline of the neck in the planar thyroid scintigraphy. However, it did not provide information about the anatomical localization of the ectopic thyroid tissue. On the other hand, ultrasonography did not provide many benefits in the differentiation of thyroglossal duct cysts and ectopic thyroid tissue. In SPECT/CT, on the other hand, the localization of the lesion, whether it is located within the cyst and its relationship with the surrounding tissue can be clearly understood.

References

1. Noussios G, Anagnostis P, Goulis DG, Lappas D, Natsis K. Ectopic thyroid tissue: anatomical, clinical, and surgical implications of a rare entity. European journal of endocrinology. 2011;165(3):375-382.

2. Rao PN, Pandit N, Kumar R, Upadhya IV, Sagar MSV. Ectopic functioning thyroid tissue in the thyroglossal duct detected by radionuclide imaging. Clinical nuclear medicine. 2005;30(9):630.