Global Gene Expression Analysis of Reactive Stroma in Prostate Cancer


Dakhova O., Ozen M. , Creighton C. J. , Li R., Ayala G., Rowley D., ...Daha Fazla

CLINICAL CANCER RESEARCH, cilt.15, ss.3979-3989, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 15 Konu: 12
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1158/1078-0432.ccr-08-1899
  • Dergi Adı: CLINICAL CANCER RESEARCH
  • Sayfa Sayıları: ss.3979-3989

Özet

Purpose: Marked reactive stroma formation, designated as grade 3 reactive stroma, is associated with poor outcome in clinically localized prostate cancer. To understand the biological processes and signaling mechanisms underlying the formation of such reactive stroma, we carried out microarray gene expression analysis of laser-captured reactive stroma and matched normal stroma.