Deficient prepulse inhibition of blink reflex in migraine and its relation to allodynia


Uygunoglu U., Gunduz A., Ertem H. D., Uluduz D., Saip S., Goksan B., ...Daha Fazla

NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY, cilt.47, sa.1, ss.63-68, 2017 (SCI-Expanded) identifier identifier identifier

Özet

Objective. - Prepulse inhibition (PPI) of the blink reflex (BR) is a reduction in BR excitability due to a conditioning stimulus, reflecting sensory gating by brainstem structures. We aimed to analyze PPI changes during a painful episode in chronic or episodic migraine and its relation to allodynia, since abnormal brainstem filtering has been hypothesized in migraine pathophysiology.