Can the nucleic acid amplification test (NAT) be an alternative to the serologic tests? A prospective study, the results of 18,200 blood donors from the Turkish Red Crescent

Kosan, Erdogan; Kocazeybek, Bekir; Altunay, Husnu; Aymelek, Meryem; Alan, Esra; Saribas, Abdulkerim; Aslan, Mustafa; Yenen, Osman; Yuksel, Pelin; Birinci, Ilhan; Kirali, Kaan; Aksoy, Armagan

doi:10.1016/j.transci.2010.09.013

Can the nucleic acid amplification test (NAT) be an alternative to the serologic tests? A prospective study, the results of 18,200 blood donors from the Turkish Red Crescent

Atıf İçin Kopyala

Kosan E., Kocazeybek B., Altunay H., Aymelek M., Alan E., Saribas S., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.43, sa.3, ss.269-272, 2010 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 43 Sayı: 3
Basım Tarihi: 2010
Doi Numarası: 10.1016/j.transci.2010.09.013
Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.269-272
İstanbul Üniversitesi Adresli: Evet

Özet

Aim: Serologic tests having high sensitivity and specificity are used in order to prevent contamination with infectious agents from blood and blood products for transfusion safety. The present serologic tests have problems such as low sensitivity and weak detection capacity of infectious agents in the "window period". We aimed to test the use of NAT (Nucleic Acid Amplification Test) in routine blood screening in the Blood Bank.