Safety of Statin Pretreatment in Intravenous Thrombolysis for Acute Ischemic Stroke


Tsivgoulis G., Kadlecova P., Kobayashi A., Czlonkowska A., Brozman M., Svigelj V., ...More

STROKE, vol.46, no.9, pp.2681-2684, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.1161/strokeaha.115.010244
  • Title of Journal : STROKE
  • Page Numbers: pp.2681-2684

Abstract

Background and Purpose-A recent meta-analysis investigating the association between statins and early outcomes in acute ischemic stroke (AIS) patients treated with intravenous thrombolysis (IVT) indicated that prestroke statin treatment was associated with increased risk of 90-day mortality and symptomatic intracranial hemorrhage. We investigated the potential association of statin pretreatment with early outcomes in a large, international registry of AIS patients treated with IVT.