The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study.

Siklar, Zeynep; Genens, Mikayir; Poyrazoglu, Şükran; Bas, Firdevs; Darendeliler, Fatma; Bundak, Ruveyde; Aycan, Zehra; Erdeve, Senay; Cetinkaya, Semra; Guven, Ayla; Abali, Saygın; ATAY, Zeynep; Turan, Serap; Kara, Cengiz; Yilmaz, Gulay; Akyurek, Nesibe; ABACI, Ayhan; Celmeli, Gamze; Sari, Erkan; BOLU, Semih; Korkmaz, Huseyin; SIMSEK, Enver; CATLI, Gonul; Buyukinan, Muammer; CAYIR, Atilla; Evliyaoglu, Olcay; Isguven, Pinar; Ozgen, Tolga; Hatipoglu, Nihal; Elhan, Atilla; Berberoglu, Merih

doi:10.4274/jcrpe.3013

The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study.

Atıf İçin Kopyala

Siklar Z., Genens M., Poyrazoglu S., Bas F., Darendeliler F. F., Bundak R., ...Daha Fazla

Journal of clinical research in pediatric endocrinology, cilt.8, sa.3, ss.305-12, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 8 Sayı: 3
Basım Tarihi: 2016
Doi Numarası: 10.4274/jcrpe.3013
Dergi Adı: Journal of clinical research in pediatric endocrinology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.305-12
Anahtar Kelimeler: Noonan syndrome, growth hormone treatment, growth, CLINICAL-FEATURES, CHILDREN, THERAPY, HEIGHT, MUTATIONS, DIAGNOSIS
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Noonan syndrome (NS) is a multisystem disorder, and short stature is its most striking manifestation. Optimal growth hormone (GH) treatment for NS is still controversial. In this study, using a nationwide registration system, we aimed to evaluate the growth characteristics and the clinical features of NS patients in Turkey and their growth response to GH treatment.