Quantitative ethnobotanical analysis and pharmacological relevance of the genus Rheum L. in Türkiye


SARI F., KOÇYİĞİT AVCI M.

Acta Pharmaceutica Sciencia, cilt.64, sa.2, ss.299-329, 2026 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 2
  • Basım Tarihi: 2026
  • Doi Numarası: 10.23893/1307-2080.aps64017
  • Dergi Adı: Acta Pharmaceutica Sciencia
  • Derginin Tarandığı İndeksler: Scopus, EMBASE
  • Sayfa Sayıları: ss.299-329
  • Anahtar Kelimeler: ethnobotany, herbal remedies, Rheum ribes, Rheum telianum, traditional knowledge
  • İstanbul Üniversitesi Adresli: Evet

Özet

In the Eastern and Southeastern Anatolia regions of Türkiye, there is a rich diversity of medicinal plants used in traditional folk medicine. Species belonging to the genus Rheum L. (R. ribes L. and R. telianum Ilcim) hold a significant place in traditional healing practices. This study aims is to comprehensively document the traditional uses of Rheum species, to evaluate their cultural importance quantitatively using ethnobotanical indices, and to contribute advanced molecular drug discovery. Fieldwork was conducted with 143 participants across seven high-altitude rural settlements in the provinces of Ağrı, Van, Şırnak, and Adıyaman, where plant samples were also collected. The collected data were analyzed using ethnobotanical criteria including Use Value (UV), Informant Consensus Factor (ICF), Cultural Importance Index (CI), and Relative Frequency of Citation (RFC). R. ribes emerged as particularly notable for its widespread use in antidiabetic, anticancer, and nutritional applications, with a high Use Value (UV = 0.71) and Relative Frequency of Citation (RFC = 0.76). A high Informant Consensus Factor (ICF > 0.99) among participants indicated a strong cultural foundation for its traditional use. The Cultural Importance Index (CI = 1.12) further supported the prominent role of R. ribes. The findings of this study demonstrate that species of the Rheum genus are used for therapeutic purposes in Türkiye. While regional diversity influences usage differences, the preservation, transmission, and quantitative compilation of traditional knowledge is of great importance from a modern pharmacological perspective.