EXPOSURE TO MELAMINE FROM THE EARLY POSTNATAL PERIOD CAUSES NEPROTOXICITY: A HISTOPATHOLOGIC AND ULTRASTRUCTURAL STUDY

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ERİŞGİN Z., MUTLU H. S.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.85, no.3, pp.433-439, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 85 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.26650/iuitfd.1074354
  • Journal Name: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.433-439
  • Keywords: Early postnatal period, electron microscopy, kidney, melamin, nephrotoxicity, rat, DOSE-RESPONSE ASSESSMENT, CYANURIC ACID, KIDNEY, NEPHROTOXICITY, FORMULA, INCREASES, TOXICITY, DAMAGE, CATS
  • Istanbul University Affiliated: Yes

Abstract

Objective: Melamine (mel), which is illegally added to formula to providing false-positive protein content, has caused acute renal failure in infants due to crystal formation. This study aimed to investigate the nephrotoxic effects of chronic low-dose mel exposure from the weaning period (supplementary food period).