Effects of menopause and postmenopausal tibolone treatment on plasma TNF alpha, IL-4, IL-10, IL-12 cytokine pattern and some bone turnover markers

Vural P. , CANBAZ M., Akgul C.

PHARMACOLOGICAL RESEARCH, cilt.53, sa.4, ss.367-371, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Konu: 4
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.phrs.2006.01.005
  • Sayfa Sayıları: ss.367-371


Objective: To asses plasma TNF alpha, IL-4, IL-10, IL-12; urinay hydroxyproline (Hyp) and calcium as bone resorption markers in healthy postmenopausal women compared with premenopausal ones, and to observe the effect of tibolone (2.5 mg/day for 6 months) upon above mentioned parameters.