Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogramming of glutamine metabolism

Weger M., Weger B. D., Goerling B., Poschet G., Yildiz M., Hell R., ...More

EBIOMEDICINE, vol.36, pp.376-389, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36
  • Publication Date: 2018
  • Doi Number: 10.1016/j.ebiom.2018.09.024
  • Journal Name: EBIOMEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.376-389
  • Istanbul University Affiliated: Yes


Background: Deficient glucocorticoid biosynthesis leading to adrenal insufficiency is life-threatening and is associated with significant co-morbidities. The affected pathways underlying the pathophysiology of co-morbidities due to glucocorticoid deficiency remain poorly understood and require further investigation.