Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogramming of glutamine metabolism

Weger, Meltem; Weger, Benjamin; Goerling, Benjamin; Poschet, Gernot; Yildiz, MELEK; Hell, Ruediger; Luy, Burkhard; Akcay, Teoman; GÜRAN, TÜLAY; Dickmeis, Thomas; Mueller, Ferenc; Krone, Nils

doi:10.1016/j.ebiom.2018.09.024

Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogramming of glutamine metabolism

Weger M., Weger B. D., Goerling B., Poschet G., Yildiz M., Hell R., ...Daha Fazla

EBIOMEDICINE, cilt.36, ss.376-389, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 36
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.ebiom.2018.09.024
Dergi Adı: EBIOMEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.376-389
İstanbul Üniversitesi Adresli: Hayır

Özet

Background: Deficient glucocorticoid biosynthesis leading to adrenal insufficiency is life-threatening and is associated with significant co-morbidities. The affected pathways underlying the pathophysiology of co-morbidities due to glucocorticoid deficiency remain poorly understood and require further investigation.