in: Upper Extremity Reconstruction From Simple to Complex, Bilsev İnce, Editor, Springer Nature Switzerland Ag, Basel, pp.339-354, 2025
Nerve transfers have become as a revolutionary technique in reconstructive surgery, offering a promising solution for reestablishing both sensory and motor functions in complex peripheral nerve injuries, brachial plexus neuropathies, and spinal cord injuries. This chapter reviews the fundamental principles and surgical approaches associated with nerve transfers, with a focus on upper extremity reconstruction. Nerve transfers provide direct reinnervation of the affected muscles, resulting in faster recovery and superior functional outcomes compared to traditional nerve grafting techniques. Key factors influencing success include the selection of appropriate donor nerves, motor synergy, and ensuring tension-free nerve coaptation. The article explores common applications, such as restoring shoulder abduction, elbow flexion, thumb opposition, and hand function, especially in cases of brachial plexus avulsions and high-grade peripheral nerve injuries. Advances in double fascicular transfers and alternative donor nerve options, such as the spinal accessory and intercostal nerves, have significantly expanded the scope of nerve transfers. Challenges associated with rehabilitation and postoperative management are also discussed, highlighting the importance of synergistic nerve choices for optimizing motor relearning. Looking ahead, continued refinement of techniques and enhanced rehabilitation protocols are expected to improve outcomes and increase patient satisfaction in the area of nerve transfer surgery.