Centaurea amanosensis M. Bona, a new species of Asteraceae from Hatay province of Turkey is described and illustrated. It is morphologically similar to C. cheirolopha (Fenzl) Wagenitz, C. lycopifolia Boiss. & Kotschy ex Boiss. & Kotschy, and C. stevenii Bieb. (Section Pseudoseridia), but it differs mainly in life form, general habit, leaves and achene characters. The IUCN conservation status of Critically Endangered (CR) should be applied to C. amanosensis.