Efficacy of tenofovir in adefovir-experienced patients compared with treatment-naive patients with chronic hepatitis B

KESKİN O., Ormeci A., Baran B., Kabacam G., Tuzun A., Karatayli E., ...Daha Fazla

ANTIVIRAL THERAPY, cilt.19, sa.6, ss.543-550, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3851/imp2732
  • Dergi Adı: ANTIVIRAL THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.543-550
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Tenofovir (TDF) has similar antiviral efficacy in both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients. Data on TDF use in patients with adefovir (ADV) resistance is inconsistent. The aim of our study was to assess antiviral efficacy of TDF against nucleoside analogue-naive (NN) and ADV-resistant (ADV-R) CHB and suboptimal responders to ADV (ADV-S).