The Association of Antibody Levels with Body Mass Index, Stress Management Ability and Lipid Peroxidation in Patients with Hashimoto’s Thyroiditis

Karpuzoğlu F. H.

The Turkish Journal of Ear Nose and Throat, cilt.33, sa.3, ss.71-75, 2023 (Hakemli Dergi)

Özet

Objective: The potential predictive value of body mass index, stress management ability, and thiobarbituric acid reactive substances (TBARS) levels for antibody levels in Hashimoto’s thyroiditis (HT) were evaluated. Materials and Methods: Two hundred patients with HT were included in the study. The patients were allocated into four groups as Group 1, patients with a body mass index (BMI) of 30 or higher (n=54); Group 2, patients with stress management difficulties (n=59); Group 3, patients with a BMI higher than 30 and stress management difficulties (n=11), and Group 4 (control, n=76), those without obesity or stress management issues. The mean age of patients, BMI, stress management abilities, anti-thyroid peroxidase (anti-TPO) antibodies levels, weekly T4 drug dosages, duration of levothyroxine usage, quality of life scores, as well as thiobarbituric acid reactive substances (TBARS) were evaluated. Results: The antibody levels were significantly associated with body mass index and stress management. The antibody level increased 533 times (p<0.0001) in the group without stress management difficulties, and was affected 525 times (p<0.0001) in the obesity group. Conclusion: The findings of our investigation revealed that stress management ability and obesity are the important factors influencing antibody levels