Cutaneous CD4+/CD56 hematodermic neoplasm


Zindanci I., Kavala M., BÜYÜKBABANİ N., Kocaturk E., Koc M.

INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, vol.76, no.6, 2010 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 6
  • Publication Date: 2010
  • Doi Number: 10.4103/0378-6323.72471
  • Journal Name: INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: CD4+/CD56+hematodermic neoplasm, blastic Natural killer cell lymphoma, natural killer lymphoma, LYMPHOMAS
  • Istanbul University Affiliated: Yes

Abstract

CD4+/CD56+ hematodermic neoplasm, formerly known as blastic NK cell lymphoma, is a rare and aggressive neoplasm with a high incidence of cutaneous involvement, risk of leukemic dissemination and poor prognosis. The characteristic features are expression of the T helper inducer cell marker CD4 and the NK-cell marker CD56 in the absence of other T cell or NKcell specific markers. Because of the rarity of this disease, we describe a 48 year old woman suffering from CD4+/CD56+ hematodermic neoplasm on her cheek without leukemic infiltration.