The ATP Assay, but not the MTT assay, Detects Further Cytotoxicity of the Combination of Anthracycline-based Therapy with Histone Deacetylase Inhibitor (Valproic Acid) in Breast Cancer Cells

ARI, FERDA; Ikitimur, Elif; ULUKAYA, Engin

The ATP Assay, but not the MTT assay, Detects Further Cytotoxicity of the Combination of Anthracycline-based Therapy with Histone Deacetylase Inhibitor (Valproic Acid) in Breast Cancer Cells

Atıf İçin Kopyala

ARI F., Ikitimur E. I., ULUKAYA E.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.35, sa.4, ss.293-299, 2010 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 35 Sayı: 4
Basım Tarihi: 2010
Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.293-299
İstanbul Üniversitesi Adresli: Evet

Özet

Purpose: It has been investigated that whether or not the combination of valproic acid (a histone deacetylase inhibitor) with anthracycline-based chemotherapy (FEC: 5-fluorouracil+epirubicine+ cyclophosphamide) would change the cytotoxic effects of FEC in breast cancer cells.