Characterization of apricot gum as a binder in tablet formulations

Şensoy D., CEVHER E., Altinkurt T.

Acta Pharmaceutica Sciencia, vol.48, no.1, pp.35-43, 2006 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 1
  • Publication Date: 2006
  • Journal Name: Acta Pharmaceutica Sciencia
  • Journal Indexes: Scopus
  • Page Numbers: pp.35-43
  • Keywords: Apricot gum, Prunus armeniaca, Tablet binder, Tenoxic, Wet granulation
  • Istanbul University Affiliated: Yes

Abstract

In this study, apricot gum (APG) obtained from Prunus armeniaca was evaluated as a tablet binder for wet granulation method. Tenoxicam (TNX) was chosen as the model drug. Binding property of APG was compared with other binding agents as gum arabic (GA) and polyvinyl pyrrolidone (PVP). The effect of different compression pressures on the properties of tablets was also investigated. Results indicated APG as a potential pharmaceutical binding agent when compared to GA and PVP.