Characterization of apricot gum as a binder in tablet formulations

Şensoy D., CEVHER E., Altinkurt T.

Acta Pharmaceutica Sciencia, cilt.48, sa.1, ss.35-43, 2006 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 1
  • Basım Tarihi: 2006
  • Dergi Adı: Acta Pharmaceutica Sciencia
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.35-43
  • Anahtar Kelimeler: Apricot gum, Prunus armeniaca, Tablet binder, Tenoxic, Wet granulation
  • İstanbul Üniversitesi Adresli: Evet

Özet

In this study, apricot gum (APG) obtained from Prunus armeniaca was evaluated as a tablet binder for wet granulation method. Tenoxicam (TNX) was chosen as the model drug. Binding property of APG was compared with other binding agents as gum arabic (GA) and polyvinyl pyrrolidone (PVP). The effect of different compression pressures on the properties of tablets was also investigated. Results indicated APG as a potential pharmaceutical binding agent when compared to GA and PVP.