Preclinical validation of a monochrome real-time multiplex assay for translocations in childhood acute lymphoblastic leukemia

SIRAJ A., OZBEK U. , SAZAWAL S., Sirma S. , TIMSON G., AL-NASSER A., ...More

CLINICAL CANCER RESEARCH, vol.8, no.12, pp.3832-3840, 2002 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 12
  • Publication Date: 2002
  • Title of Journal : CLINICAL CANCER RESEARCH
  • Page Numbers: pp.3832-3840

Abstract

Purpose: The purpose is to develop a real-time multiplex reverse transcription-PCR assay for detection and quantification of leukemia-specific chimeric transcripts that identify the genetic subgroups of acute lymphoblastic leukemias (ALLs) proposed by the WHO classification.